TOPOSYM is a series of international topology conferences held in Prague, Czech Republic in a five year cycle since 1961. Topics of the conference include general and set-theoretical topology, descriptive set theory, continuum theory, topological dynamics, topology in functional analysis, topology in algebra, and categorial topology. TOPOSYM 2016 was held on July 25–29, 2016 in Prague, Czech Republic under the auspices of the Institute of Mathematics of the Czech Academy of Sciences and the Faculty of Mathematics and Physics of the Charles University.

The following mathematicians presented a plenary talk.

- Alexander Arhangel'skii (Ohio University, USA & University of Moscow, Russia)
- Leandro Aurichi (Departamento de Matemática, Universidade de São Paulo, Brasil)
- Dikran Dikranjan (University of Udine, Italy)
- Alan Dow (University of North Carolina at Charlotte, USA)
- Michael Hrušák (National Autonomous University of Mexico)
- Ondřej Kalenda (Charles University in Prague, Czech Republic)
- Alexander Kechris (California Institute of Technology, USA)
- Piotr Koszmider (Mathematical Institute of the Polish of Academy of Sciences)
- Mikolaj Krupski (University of Warsaw, Poland)
- Wieslaw Kubis (Institute of Mathematics of the Czech Academy of Sciences)
- Aleksandra Kwiatkowska (University of Bonn, Germany)
- Jordi Lopez-Abad (Institute of Mathematical Sciences, Madrid, Spain)
- Veronica Martinez de la Vega (National Autonomous University of Mexico)
- Julien Melleray (Institut Camille-Jordan, Université Lyon 1, France)
- Jan van Mill (University of Amsterdam, Netherlands)
- Arnold Miller (University of Wisconsin–Madison, USA)
- Justin Moore (Cornell University, Ithaca, New York, USA)
- Chris Mouron (Rhodes College, Memphis, Tennessee, USA)
- Lionel Nguyen Van Thé (Institut de Mathématiques de Marseille, Université d'Aix–Marseille, France)
- Lex Oversteegen (University of Alabama at Birmingham, USA)
- Christian Rosendal (University of Illinois at Chicago, USA)
- Marcin Sabok (McGill University, Montreal, Canada)
- Slawomir Solecki (University of Illinois at Urbana–Champaign, USA)
- Lajos Soukup (Alfréd Rényi Institute of Mathematics, Hungarian Academy of Sciences)
- Mikhail Tkachenko (Metropolitan Autonomous University, Iztapalapa, Mexico)
- Stevo Todorcevic (University of Toronto, Canada and Institut de Mathématiques de Jussieu, Paris, France)
- Toshimichi Usuba (Kobe University, Japan)
- Benjamin Weiss (Hebrew University of Jerusalem, Israel)

- Bohuslav Balcar (Institute of Mathematics of the Czech Academy of Sciences)
- Christina Brech (Departamento de Matemática, Universidade de São Paulo)
- K. P. Hart (Department of Mathematics, Delft University of Technology)
- Logan Hoehn (Department of Computer Science and Mathematics, Nipissing University)
- Petr Simon (Faculty of Mathematics and Physics, Charles University in Prague)
- Todor Tsankov (Institut de Mathématiques de Jussieu, Université Paris Diderot)
- Lyubomyr Zdomskyy (Kurt Gödel Research Center, University of Vienna)

- David Chodounský (Institute of Mathematics of the Czech Academy of Sciences)
- Jan Starý (Department of Mathematics, Czech Technical University)
- Benjamin Vejnar (Faculty of Mathematics and Physics, Charles University in Prague)